Children
I want your sex
How ethical is it to choose the sex of your baby, and what does it mean for the future of the human race?
When I was 4, my mom announced that she was pregnant. I was ecstatic
– finally I’d have the little brother I’d always wanted. There was no
doubt in my child-mind that the baby would be a boy. My parents already
had a girl, so why would they need another one? I just assumed they
would ask the baby gods for a boy and be granted their wish.
Needless to say, when my sister was born, I was devastated. I
had been replaced by a gurgling bundle of joy who, by all accounts, had
the rosy cheeks and ringlets of an earthbound angel. I couldn’t hack
the competition. I packed my suitcase and tearily headed out the door,
a self-proclaimed orphan.
I eventually got over my replacement complex and learned to love my
little sister. A natural selection was made and now I can’t imagine life
without her. But for those older siblings — and parents-to-be — who
want to challenge nature, a formidable weapon is at hand. Last week,
doctors at the Genetics & IVF Institute in Fairfax, Va., led by Dr.
Edward Fugger, announced that they can sort sperm in such a way that
will allow couples to choose the sex of their babies. But how ethical is
gender selection, and is it safe?
Couples who entered the trial either wanted to prevent sex-linked
disorders or simply wanted to do a little gender balancing within the
family. In fact, 90.5 percent of the study’s participants had already
given birth to two or three sons and wanted their final child to be a
daughter.
Using a process called flow cytometric separation — branded
MicroSort — doctors were able to increase the number of X-chromosomes
(female) in any given sorted sperm sample to 85 percent, vs. the
approximately 50 percent contained in a normal sperm specimen. That
means that couples who use a sorted sperm sample are five to six times
more likely to have a female child than a male child. A total of 29
pregnancies by intrauterine insemination (IUI), in-vitro fertilization
(IVF) and intracytoplasmic sperm injection (ICSI) resulted during the
trial. Of the 14 pregnancies in which the gender of the fetus or child
has been determined, 13 are female. That’s a 92.9 percent success rate.
The Amazon women’s lost civilization has a chance at resurrection yet.
For couples who run the risk of passing on genetic, sex-linked
diseases to their children, gender selection is a boon. Disorders like
hemophilia and muscular dystrophy, two diseases most prevalent among
males, could be avoided by tilting the content of a man’s sperm to favor
the X chromosome. Here the request for sex selection is justified for
health reasons. But for people who simply desire to give birth to one
gender over another, the ethical lines become blurry. If you’re
religious, fooling with nature goes against the domain of God; if you’re
not, you might get a thrill out of cheating Lady Luck. While it might
seem fun to predetermine the sex of your baby, the bottom line is that
sex selection could theoretically lead to the demise of the human race.
If too many people choose one gender over another, we could be in big
trouble.
But it depends on how many people really want to select their
child’s gender, says Dr. Alan DeCherney, chairman of the Department of
Obstetrics and Gynecology at UCLA. His feeling is that not a lot of
people really want to interfere with
nature, at least not in the United States. But what about people in
other countries, like China, where male babies are historically more
valued than female ones? Well, the MicroSort study won’t be of much use
to Chinese couples since the only conclusive data shows that sperm can
be sorted for female selection, not male. Unpublished data shows that
the MicroSort technology can increase the average content of Y-bearing
sperm to 65 percent from the normal 50 percent. However, this theory has
not been fully tested.
In addition to the ethical questions surrounding gender selection,
there’s also the issue of whether the flow cytometric separation
of sperm cells is a safe process. To date, the only way to tell the
difference between living X- and Y-bearing sperm is by their total DNA
content: X chromosomes have 2.8 percent more DNA content than Y
chromosomes. In order to sort the sperm, fresh and frozen samples are
liquefied, then evaluated for volume, count, motion, development,
viability and percent of abnormal cells using World Health Organization
standards. Samples are then extended, centrifuged, resuspended and
filtered through glass wool to remove debris and bum cells (good thing
they don’t do this while the sperm’s still in its natural environment).
They are then stained with a fluorescent substance that finds female
chromosome-bearing sperm cells according to their weight and marks them
with a pink spot. To see the different sperm, the sample is exposed to
ultraviolet rays and passed through a fluorescence activated cell
sorter.
The potential danger lies with the process of staining the sperm and
then exposing them to a laser. Some geneticists are concerned that the
substance used to mark sperm cells could cause genetic mutations in
those cells. And piercing sperm with a laser might nick the DNA. While
this is the first time the MicroSort technology has been applied to
humans, according to the report, all the resulting births so far have
been of normal, healthy babies. Now we can finally join the illustrious
ranks of the bovine, swine, ovine and rabbit, all unwitting test
subjects in the name of human sex selection. More than 400 normal
offspring were produced by these four animal species before the process
was used with humans.
So if you’re a mom who loves her little boys but yearns for a
daughter, you might be interested in undergoing the MicroSort treatment.
In that case, get ready to pay up. The Genetics & IVF Institute is
currently the only place where the process is available, and it charges
approximately $1,600 per cycle, according to DeCherney. A cycle is
defined as an attempt to become pregnant via IUI, IVF or ICSI. The
number of cycles it takes any one individual to conceive depends on
several factors, including age, type of insemination procedure and
quality of the semen specimen. The average age of
the couples in the study was 33.9 years and the most successful method
of insemination was IUI. Just make sure your stud doesn’t deplete his
sperm count by wearing tighty-whiteys, and a daughter is practically
guaranteed.
Lisa Moskowitz writes and lives in San Francisco. Her work has appeared in Adweek, PC World Online, MyLifePath.com and American Kite magazine. More Lisa Moskowitz.
Saturday Morning Gift
A short film based on a real interview with a young boy who survived the 2006 war in Lebanon
Filmmaker Bassel Shahade, who directed “Saturday Morning Gift,” is 28 years old, a graduate of Syracuse University’s School of Visual and Performing Art and a very brave young filmmaker. Unfortunately, he is also missing. Shahade traveled to Syria to document the unrest and, he hasn’t been heard from in months. If you have any information on his whereabouts, please notify us via studio [at] salon.com.
A death that was also a birth
As a midwife, I've spent the last 30 years taking care of women in pregnancy. But nothing prepared me for this
(Credit: Clara via Shutterstock) The call came early in the morning. The 3-month-old granddaughter of my neighbor had finally succumbed to the illness she was born with. I am a midwife, but this call wasn’t about a birth. This time the call was from the mortuary.
I have spent the last 30 years taking care of women in pregnancy, birth and beyond. I use my hands to help bring life into this world. Over the past few years, however, I found myself using those very same hands in the performance of a Taharah, a Jewish ritual that prepares a dead woman for burial. Birth, life, joy, beginnings vs. death, decay, finality. Such a contrast! What could be more different? And yet, somewhere in my consciousness, there was a commonality. Caring for a woman in her life, preparing a woman for birth had a parallel in preparing a woman for burial. The act of helping a woman and her baby through their many transitions seemed analogous to helping the soul transition from this plane of existence to the next.
Continue Reading CloseTova Hinda Siegel is a writer who lives in Los Angeles. More Tova Hinda Siegel.
“Why won’t you answer me?”
Kids' questions may be annoying -- but they're more crucial to learning than we've ever thought. An expert explains
(Credit: Bonita R. Cheshier via Shutterstock) Children can ask a lot of very annoying questions. Starting at about 2 years of age, they begin barraging their parents with endless queries, from “Are we there yet?” to “Why is the moon round?” — questions that often seem more like desperate ploys for parental attention than anything else. And, to make things worse, cooperative parents are often treated to a relentless barrage of follow-up questions, many of which involve one word: “Why?” Is this process infuriating? Yes. But is it crucial to their development? Far more than most of us think. And furthermore, the frequency and form of those questions can tell us a lot, not only about how children learn but also about cultural and class differences in America.
Continue Reading Close
Thomas Rogers is Salon's Arts Editor. More Thomas Rogers.
Child acting’s new golden age
From Chloe Grace Moretz to "Shameless," kids aren't just getting more roles -- they're actually good. What changed?
Chloë Moretz in "Hick" “Never work with children or animals” is an old W.C. Fields chestnut that, for a while in the ’90s and ’00s, everyone outside of children’s entertainment seemed to be holding sacred. Child actors were off on their own in a parallel entertainment universe created by Disney and Nickelodeon, while adults held down the fort in dramas and reality shows. There were some notable exceptions, like Haley Joel Osment and Christina Ricci, but by and large, children were almost entirely absent from grown-up entertainment.
Continue Reading CloseMichael Barthel is a PhD candidate in the communication department at the University of Washington. He has written about pop music for the Awl, Idolator, and the Village Voice. More Michael Barthel.
My dad’s 30-year coming out
I thought my father kept secrets because he was gay. Turns out all parents have a walled-off life -- and that's OK
Gideon Lewis-Kraus (Credit: Rose Lichter Marck) I must’ve been eight or nine the one time my dad took me along to meet Bart. This was somewhere near Tompkins Square Park. What I recalled was a shaggy shock of blue hair, and feelings of both elation and terror: On the one hand thrilled to be old enough to be taken along one night to the city to meet a guy with blue hair, and on the other frightened of the jagged dark in the Alphabet City of the late ’80s. In my memory Bart looked like Warhol, but maybe that was just part of the dream pedigree I had for my dad, the one that looked to White and Genet and not “Will & Grace.” But I did think that my dad once said he’d gone with Bart to sell drugs to Allen Ginsberg, so maybe in this case my retrospective fantasy — that if he’d had a secret life, it could at least have been an exciting one, something worth escaping his surface life for — was accurate. I remembered hearing for the first time about AIDS, and I remembered my dad walking around for some months, maybe years, as though accompanied by ghosts. It was selfish and obscene for me to look back and want his secrets, the secrets I’d come here to try to clear up, to have hidden amazing things: It meant I have at best ignored and at worst aestheticized the fact of what must have been unimaginable pain. Like any gay man of his age, he’d watched a great number of his close friends die of AIDS, but unlike many of those men, he was not able to talk about it to the people closest to him, the people he lived with. Maybe the reason he liked “Will & Grace” and not so much White and Genet — though, now that I think of it, I did give him “The Married Man” once and he told me it was the best novel he’d ever read — was that all he wants now is to be normal and happy. He wanted to marry Brett and drink boxed wine and take Yoshi out for walks and watch “Mamma Mia!” until their DVD player caught fire. I myself had never been less than loathsome on the subject of “Mamma Mia!” and I felt terrible about it, but I didn’t want to digress into overemphatic apology, and I would stand by my derision of “Mamma Mia!”
Continue Reading CloseGideon Lewis-Kraus is the author of "A Sense of Direction: Pilgrimage for the Restless and Hopeless." He has written for Harper's, the Believer, McSweeney's, Bookforum and other publications. More Gideon Lewis-Kraus.
Page 1 of 67 in Children