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Mary Papenfuss

Monday, Dec 9, 2002 8:49 PM UTC2002-12-09T20:49:00Zl, M j, Y g:i A T

The patient or the portfolio?

A growing number of medical researchers have a financial stake in the experimental drugs they administer. The resulting conflict of interest can be decidedly unhealthy for their patients.

The patient or the portfolio?

Five years ago, terminal cancer patients were given hope that a longer life — possibly even a cure for the disease — could be within reach. Researchers at several hospitals, including the M.D. Anderson Cancer Center at the University of Texas in Houston, were conducting trials on what was being regarded as something of a cancer wonder drug — an agent that appeared to successfully block a growth factor that turns cells malignant. Abdominal tumors nearly disappeared in a 28-year-old Miami woman taking the drug.

But this year the Miami woman died, months after the federal Food and Drug Administration rejected the application for the drug’s approval, saying some clinical tests designed by the manufacturer had flaws that failed to prove the drug’s effectiveness.

The drug was Erbitux, the company ImClone Systems. The FDA’s rejection sent ImClone’s stocks into a nosedive, and an insider-trading scandal erupted. Only then did the 195 patients who participated in clinical trials at M.D. Anderson learn that its president, John Mendelsohn, held a major stake in ImClone and sat on its board of directors at the same time his researchers were testing the company’s drug.

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Thursday, Nov 16, 2006 1:08 PM UTC2006-11-16T13:08:00Zl, M j, Y g:i A T

The French Hillary

In this political power couple, it's the woman who gets the first shot at being president.

The French Hillary

Imagine, if you will, a parallel universe, where a female politician’s four out-of-wedlock children charm the voting public, where her bikini-worthy 53-year-old body is a valuable political asset, and where she is likely to become president before her more powerful male partner, the fellow politician with whom she had those kids.

Welcome to the twilight zone, France, and the Gallic version of political power couple Hillary and Bill Clinton. After last Tuesday, Hillary Clinton’s chances of following her husband to the White House are looking rosier. In France, however, her counterpart is only a day away from becoming her party’s official nominee for the presidency. And the French Hillary’s romantic partner, an unsuccessful candidate for the same post, will be relegated to the sidelines.

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Friday, Apr 7, 2006 10:07 AM UTC2006-04-07T10:07:00Zl, M j, Y g:i A T

Paris is burning

The French protests involve more than just job security for young workers. They're a battle for the soul of the European Union.

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Baby revolutionaries Étienne Phillip, 16, and 17-year-old Christiane T. are lounging on the metal chairs along the boat pond in the Jardin du Luxembourg, ready for their next demonstration. Blocks away a phalanx of cops stand guard behind stanchions blocking access to the Sorbonne. The teens are part of one of several clusters of young people in the park highlighting book passages, writing reports and playing cards because they’ve been locked out of nearby high schools and universities in the wake of protests against the new French labor contract that would make it easy to fire young workers.

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Thursday, Apr 24, 2003 7:50 PM UTC2003-04-24T19:50:00Zl, M j, Y g:i A T

Pro-choice groups agonize over fetal murder law

When a NOW leader said charging Scott Peterson for the murder of his unborn son threatened abortion rights, even some feminists were horrified. But that's been pro-choice orthodoxy on fetal-rights laws -- until now.

When Mavra Start, head of the Morris County, N.J., chapter of the National Organization for Women (NOW), told a local newspaper that charging Scott Peterson with double murder in the death of his wife Laci and unborn son Conner could aid the antiabortion movement, she was blindsided by fierce criticism — some of which came from feminists. In less than 24 hours, Start backed off from her comments, saying that she was merely “thinking out loud.”

The conflict raised by the double murder charges against is a painful one, made worse by the obvious suffering of the young woman’s family. But the quiet controversy around a California law that recognizes a fetus as a full-fledged murder victim raises a fundamental question that threatens to split the feminist movement as it battles to maintain a woman’s legal right to abortion: Do laws that criminalize fetal harm encroach on the rights of the mother?

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Friday, Apr 4, 2003 11:03 PM UTC2003-04-04T23:03:00Zl, M j, Y g:i A T

Can this marriage be saved?

An expert says the U.S. and the U.N. may be at each other's throats right now, but they need each other too much to break up.

The United Nations Security Council: Can’t live with it, can’t live without it.

Such is the quandary facing the Bush administration as it attempts to wrangle aid from the United Nations for reconstruction of post-invasion Iraq while ceding little control in the region. The United Nations, meanwhile, has its own dilemma: How does it respond to chaos and human suffering in Iraq after a war fiercely opposed by certain members of its Security Council, while maintaining some semblance of legitimacy and control?

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Thursday, Mar 6, 2003 7:34 PM UTC2003-03-06T19:34:00Zl, M j, Y g:i A T

Building a better war

As the U.S. marches toward an invasion of Iraq, Human Rights Watch is trying to do what critics say is impossible: Wield public opinion to create a more humanitarian war.

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Human Rights Watch is nothing if not pragmatic.

The New York-based organization, which investigates human rights abuses worldwide by traveling to trouble spots to interview victims and witnesses, vehemently opposes human rights abuses — yet also seeks dialogue with governments guilty of gross violations, and dictators that other human rights groups won’t deal with. When total compliance with international law is unattainable, HRW battles for degrees of improvement.

So while antiwar activists are pouring into the streets to protest America’s threatened invasion of Iraq, Human Rights Watch (HRW) has taken a proactive role in its own unusual gray area of warfare. Rather than trying to block an Iraqi invasion, or even arguing against it, HRW has, in effect, been trying to build a better war in Iraq. It’s not so much supporting the unthinkable, the group insists, as attempting to mitigate the damage of what may be inevitable.

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