SALON

Thursday, Jan 3, 2013 1:52 PM UTC

Study: Alzheimer’s linked to brain changes at birth

New research suggests prenatal brain development may be an important factor in psychiatric risk in adults

By

Topics: Alzheimer's Disease, Science, Brain development, ,

Study: Alzheimer's linked to brain changes at birth

Researchers at the University of North Carolina school of Medicine have found that certain brain patterns in adults with Alzheimer’s disease, schizophrenia and autism can also be seen in the brain scans of infants.

“These results suggest that prenatal brain development may be a very important influence on psychiatric risk later in life,” said lead author of the study and assistant professor of psychiatry at UNC, Rebecca C. Knickmeyer. In addition to early detection, the study may also lead to early intervention breakthroughs in the degenerative brain disorder.

According to the report on UNC’s website:

The study included 272 infants who received MRI scans at UNC Hospitals shortly after birth. The DNA of each was tested for 10 common variations in 7 genes that have been linked to brain structure in adults. These genes have also been implicated in conditions such as schizophrenia, bipolar disorder, autism, Alzheimer’s disease, anxiety disorders and depression.

For some polymorphisms – such as a variation in the APOE gene which is associated with Alzheimer’s disease – the brain changes in infants looked very similar to brain changes found in adults with the same variants, Knickmeyer said. “This could stimulate an exciting new line of research focused on preventing onset of illness through very early intervention in at-risk individuals.”

Experts say that Alzheimer’s early intervention offers far more than just the obvious health benefits — there are economic and social gains, too. Currently, there are 5.4 million Americans living with the disease, and a majority of them receive a late diagnosis, if they receive any diagnosis at all. The result is a so-called treatment gap that limits their access to critical information, proper care and community support. This not only hurts the patient, but their families and caregivers as well.

h/t Science Codex

Continue Reading Close

More Katie Mcdonough.

Next Article

Related Stories

Featured Slide Shows

What To Read Awards: Top 10 Books of 2012 slide show

close X
  • Share on Twitter
  • Share on Facebook
  • Thumbnails
  • Fullscreen
  • 1 of 10
  • 10. "The Guardians" by Sarah Manguso: "Though Sarah Manguso’s 'The Guardians' is specifically about losing a dear friend to suicide, she pries open her intelligent heart to describe our strange, sad modern lives. I think about the small resonating moments of Manguso’s narrative every day." -- M. Rebekah Otto, The Rumpus

  • 9. "Beautiful Ruins" by Jess Walter: "'Beautiful Ruins' leads my list because it's set on the coast of Italy in 1962 and Richard Burton makes an entirely convincing cameo appearance. What more could you want?" -- Maureen Corrigan, NPR's "Fresh Air"

  • 8. "Arcadia" by Lauren Groff: "'Arcadia' captures our painful nostalgia for an idyllic past we never really had." -- Ron Charles, Washington Post

  • 7. "Gone Girl" by Gillian Flynn: "When a young wife disappears on the morning of her fifth wedding anniversary, her husband becomes the automatic suspect in this compulsively readable thriller, which is as rich with sardonic humor and social satire as it is unexpected plot twists." -- Marjorie Kehe, Christian Science Monitor

  • 6. "How Should a Person Be" by Sheila Heti: "There was a reason this book was so talked about, and it’s because Heti has tapped into something great." -- Jason Diamond, Vol. 1 Brooklyn

  • 4. TIE "NW" by Zadie Smith and "Far From the Tree" by Andrew Solomon: "Zadie Smith’s 'NW' is going to enter the canon for the sheer audacity of the book’s project." -- Roxane Gay, New York Times "'Far From the Tree' by Andrew Solomon is, to my mind, a life-changing book, one that's capable of overturning long-standing ideas of identity, family and love." -- Laura Miller, Salon

  • 3. "Billy Lynn's Long Halftime Walk" by Ben Fountain: "'Billy Lynn's Long Halftime Walk' says a lot about where we are today," says Marjorie Kehe of the Christian Science Monitor. "Pretty much the whole point of that novel," adds Time's Lev Grossman.

  • 2. "Bring Up the Bodies" by Hilary Mantel: "Even more accomplished than the preceding novel in this sequence, 'Wolf Hall,' Mantel's new installment in the fictionalized life of Thomas Cromwell -- master secretary and chief fixer to Henry VIII -- is a high-wire act, a feat of novelistic derring-do." -- Laura Miller, Salon

  • 1. "Behind the Beautiful Forevers" by Katherine Boo: "Like the most remarkable literary nonfiction, it reads with the bite of a novel and opens up a corner of the world that most of us know absolutely nothing about. It stuck with me all year." -- Eric Banks, president of the National Book Critics Circle

  • Recent Slide Shows

  • Share on Twitter
  • Share on Facebook
  • Thumbnails
  • Fullscreen
  • 1 of 10

Related Videos

More Related Stories

Comments

 0 Comments

Comment Preview

Your name will appear as username ( profile | log out )

You may use these HTML tags and attributes: <a href=""> <b> <em> <strong> <i> <blockquote>

follow salon

Most Read

From Around the Web

Recommendations