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Whatever happened to last year's breakout stars?
A Boston hospital is starting the world’s first hand transplant program for children, and doctors say it won’t be long until face transplants and other radical operations to improve appearance and quality of life are offered to kids, too.
The move shows the growing willingness to do transplants to enhance a patient’s life rather than to save it as donated hearts, livers and other organs have done in the past. More than 70 hands and at least 20 faces have been transplanted in adults, and doctors say it’s clear these operations are safe enough to offer to children in certain cases, too.
“We feel that this is justifiable,” Dr. Amir Taghinia said of the pediatric hand program he will lead at Boston Children’s Hospital.
“Children will potentially benefit even more from this procedure than adults” because they regrow nerves more quickly and have more problems from prosthetic hands, he said.
Only one hand transplant is known to have been done in a child — a baby in Malaysia in 2000. Because the donor was a twin who died at birth, her sister did not need to take drugs to prevent rejection.
That’s the main risk in offering children hand transplants — the immune-suppressing drugs carry side effects and may raise the risk of cancer over the long term.
However, one independent expert thinks the gains may be worth it in certain cases.
“We understand so much more about immune suppression” that it’s less of a risk to put children on it, said Dr. Simon Horslen, medical director of the liver and intestine transplant program at Seattle Children’s Hospital. “This is never going to be done as an emergency procedure, so the families will have plenty of opportunity to weigh the options.”
Also, a hand can be removed if rejection occurs, and that would not leave the child worse off than before the transplant, Horslen said.
Several types of kids might be candidates — those born without hands, children who lose them in accidents and children with infections that wind up requiring damaged hands to be amputated.
Quality of life is a key concern for people missing arms and hands — prosthetics for those limbs are not as advanced as those for feet and legs. In December, doctors at Johns Hopkins Hospital in Baltimore did a double-arm transplant for former soldier Brendan Marrocco, who lost all four limbs while serving in Iraq. It was the seventh double-hand or double-arm transplant performed in the U.S.
For a child missing two hands, “the quality-of-life issues are a big deal,” said Dr. Douglas Diekema of the Center for Pediatric Bioethics at Seattle Children’s Hospital and a member of the American Board of Pediatrics’ ethics committee.
“In terms of how we interact with the social world, it’s mostly our face and our hands,” so a transplant “is a reasonable thing to offer a family,” he said.
Boston Children’s Hospital plans to make its first cases healthy children 10 or older who are missing both hands.
“Some of them can’t feed themselves, they can’t go to the bathroom, someone needs to assist them with almost every activity,” Taghinia said.
The hospital also will consider children missing one hand who already are taking immune-suppressing drugs because of transplanted organs, or those with only one hand that doesn’t work well.
The hospital will cover the cost of the operation and care for three months afterward, then ask insurers to pay for immune suppression and follow-up.
Boston program: http://www.bostonchildrens.org/handtransplant
Support groups: http://www.helpinghandsgroup.org/
Marilynn Marchione can be followed at http://twitter.com/MMarchioneAP
The star of “Beasts of the Southern Wild” charmed practically everyone at the Oscars, where she was the youngest best actress nominee ever; she went on to film a remake of “Annie” opposite Jamie Foxx and Cameron Diaz.
Carly Rae Jepsen
Jepsen, who had 2012’s song of the summer with “Call Me Maybe,” released the fifth and final single from her debut album in January 2013. She toured the U.S. in mid-2013 -- just as Daft Punk and Robin Thicke battled to succeed her as icons of the summer.
Honey Boo Boo
2012’s biggest reality star, the young pageant contestant Alana Thompson, had a quieter time this year, with a second season whose ratings were strong but whose buzz was a bit muted. America was, by now, accustomed to young Thompson, and outraged or scandalized reactions were reserved for other TLC programming, like “The Man With the 132-Pound Scrotum.”
Ocean missed out on the top Grammys for which he was nominated in early 2013; he bounced back quickly with featured appearances on albums by Kanye West, Jay Z and Beyoncé, and is at work on a new album. Things are looking up!
The “21 Jump Street” and “Magic Mike” star had a marginally less charmed 2013, with “White House Down” failing to connect with moviegoers and “Foxcatcher” delayed until next year. It may get worse before it gets better: His big 2014 sci-fi flick, “Jupiter Ascending,” looks … well, a little weird!
With their third album in 21 months hitting No. 1 immediately upon its fall 2013 release, the boy band that broke into America in 2012 would seem to be here to stay for a while. Still, they looked a bit nervous in their reaction shots during the Video Music Awards’ ‘N Sync reunion; maybe not this year, maybe not next, but eventually, the Justin of One Direction is going to break out. For now, though, things look good!
Lana Del Rey
The famously uncomfortable “Saturday Night Live” musical guest overcame endless mockery from 2012 to land her first top-10 hit in the summer of 2013 -- a remix of a year-old song, “Summertime Sadness.” As the co-writer of “Young and Beautiful,” the love theme from “The Great Gatsby,” Del Rey is such a front-runner for the best original song Oscar (last won by Adele) that there has been a direct-mail campaign to academy voters against her. The song was also played at the most romantic event of the year: Kanye West’s stadium marriage proposal to Kim Kardashian.
Wilson, who charmed fans of 2012’s “Pitch Perfect,” had a rockier 2013, with her sitcom “Super Fun Night” struggling creatively and in the ratings. Her next planned movies are both sequels, to “Kung Fu Panda” and -- hoping lightning will strike twice -- to “Pitch Perfect.”
Another 2012 music icon, Gotye won the record of the year trophy at the 2013 Grammys for “Somebody That I Used to Know.” He released no new singles in 2013, and has told the press he has been struggling to complete new material. Good luck, Gotye!
The golden boy of the 2012 Olympics, without feats of aquatic derring-do to distract the public this year, saw his always-tenuous persona completely shift from “amiable jock” into “utter dolt” with his E! reality series. Worst of all, the series was canceled.
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The breakout bikini model of 2012 made a repeat appearance on the cover of the Sports Illustrated swimsuit issue -- and got to do high-fashion spreads in Elle, Vogue and Vanity Fair. She was cast in a Cameron Diaz comedy, too. Some types of appeal are eternal!
E. L. James
The “50 Shades” novelist now gets to help share some input into a movie adaptation set for release in 2015. She probably never needs to work again! Isn’t that great? Isn’t that … just … great?
The “Gangnam Style” phenom performed at New Year’s 2013, but will spend New Year’s 2014 flipping channels to find his pistachio ad, his goofy antics having been outdone in the past year by “The Fox” singers Ylvis. Nothing meme can stay.
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