Search  About Salon  Table Talk  Newsletters  Advertise in Salon  Investor Relations

 
 

Salon.com

[Arts & Entertainment][ Books ][ Comics ][ Mothers Who Think ][ News ][ People ][ Politics ][ Sex ][ Technology ][ Audio ]

Article Finder



 

Decoding the genome | 1, 2, 3, 4, 5, 6


Singer is a self-described "consequentialist," a descendant of John Stuart Mill's utilitarianism and William James' pragmatism. Utilitarianism's guiding belief is that reason can determine which actions will result in the greatest happiness for the greatest number of people. Singer's reason informs him that his own self-interest is best served by this ethical approach, not only toward all people but toward all sentient beings.

Singer also believes that we should not fear scientifically based programs of genetic improvement but instead ask how they might contribute to the greatest happiness. Genetic improvement, says Singer, holds out the prospect "of a new kind of freedom." After all, if human nature is the major obstacle to creating a better society, then the solution may ultimately lie in altering that genetically based nature.



Cracking the Genome: Inside the Race to Unlock Human DNA

By Kevin Davies

The Free Press
288 pages
Nonfiction

Buy it


Genome: The Autobiography of a Species in 23 Chapters

By Matt Ridley

HarperCollins
352 pages
Nonfiction

Buy it


The Triple Helix: Gene, Organism and Environment

By Richard Lewontin

Harvard Univ. Press
192 pages
Nonfiction

Buy it


A Darwinian Left: Politics, Evolution and Cooperation

By Peter Singer

Yale Univ. Press
64 pages
Nonfiction

Buy it


Engineering the Human Germline: An Exploration of the Science and Ethics of Altering the Genes We Pass to Our Children

Edited by Gregory Stock and John Campbell

Oxford Univ. Press
208 pages
Nonfiction

Buy it


The Second Creation: Dolly and the Age of Biological Control

By Ian Wilmut Keith Campbell and Colin Tudge

Farrar, Straus and Giroux
320 pages
Nonfiction

Buy it



Print story


E-mail story


View Salon privately with SafeWeb


What makes Singer so provocative is that he takes up the left's commitment to fighting injustice and at the same time urges scientists to pursue the knowledge and control of our biological makeup to the furthest reaches. He synthesizes, in a way, the determinism of Ridley with the social commitment of Lewontin. But, at least in this work, he doesn't clarify who'll be in charge of deciding which policies will lead to the greatest happiness for the most people -- a key question, particularly given Singer's controversial advocacy of euthanasia for those born with severe mental disabilities.

In Singer's preferred social order, molecular biologists like James Watson would be free to do what they wanted. To see why this is troubling, look to Watson himself and the other contributors to "Engineering the Human Germline: An Exploration of the Science and Ethics of Altering the Genes We Pass to Our Children." This book of essays, compiled and edited by UCLA neurobiologist John Campbell and the director of the UCLA Medicine, Technology and Society Program, John Stock, also contains the fascinating transcript of a 1998 panel discussion about how far we should go in modifying genes in the sperm and eggs we use to produce future generations -- what scientists call the "human germline." Currently, almost all clinical trials of genetic therapy are directed at specific parts of the body and affect only the patient involved; germline therapy would alter the genes passed on to all future generations. Earlier this year, the American Association for the Advancement of Science issued a report recommending that any effort to proceed with germline engineering, whether in the public or private sector, be regulated.

Watson, the co-discoverer of the double helix structure of DNA, appears in his catalytic prime here, casting aside what he views as the "prejudices" of social and moral concerns in order to advance science and medicine. Not only should we "try germline therapy without completely knowing that it's going to work," Watson says, but "if we could make better human beings by knowing how to add genes, why shouldn't we do it? What's wrong with it? Who is telling us not to do it? I mean, it just seems obvious now."

Watson suggests that just as we might find benefit from putting a Brazil nut gene in a soybean to enhance its nutritional value or an Arctic fish gene in a strawberry to help it resist damage from freezing weather, so too the human genome might be improved with the implantation of a plant gene or an animal gene or perhaps even an artificially devised gene. After all, Watson says, "we [molecular biologists] should be proud of what we're doing and not worry about whether we're destroying the genetic patrimony of the world, which is awfully cruel to too many people." While some voices in "Engineering the Human Germline" recommend a less ambitious approach to modification of the human genome, Watson's fellow panelists and many of the book's essays mostly echo his views.

Ian Wilmut, the leader of the team of scientists who cloned the sheep Dolly and a scientist who nearly equals Watson in stature, proposes a moral alternative. As coauthor of "The Second Creation: Dolly and the Age of Biological Control," Wilmut shows a humility in the face of our potential ability to alter the genome that's the opposite of Watson's brashness in every way.

 

. Next page | Cloning pioneer opposes tinkering with genome
1, 2, 3, 4, 5, 6



 



Don't get sunburned!  Cover up with a Salon T-shirt this summer.




Extra goodies and great services in
Salon Plus

____
 




 
 
____
 
   
 
____
 
  Current Stories
  • The Holocaust memoir so heartwarming it had to be fake Herman Rosenblat's concentration-camp romance duped Oprah, among many others. Why are we so eager to put a happy ending on a tragedy?
    By Lev Raphael
  • How to live what Michael Pollan preaches Mark Bittman's revolutionary "Food Matters" is both a cookbook and a manifesto that shows us how to eat better -- and save the planet.
    By Laura Miller
  • Read it and weep The economic news couldn't be worse for the book industry. Now insiders are asking how literature will survive.
    By Jason Boog
  • My life in karaoke Author Brian Raftery explains how a Japanese novelty has gone from punch line to worldwide pop-culture phenomenon.
    By Sarah Hepola
  •  

    shim shim shim shim shim shim shim
    shim
    shim

    Maya Angelou reads from "The Heart of a Woman"

    shim
    shim



    Salon  Search  About Salon  Table Talk  Newsletters  Advertise in Salon  Investor Relations


    Arts & Entertainment | Books | Comics | Mothers Who Think | News
    People | Politics | Sex | Tech & Business and The Free Software Project
    Letters | Columnists | Salon Plus | Salon Shop


    Reproduction of material from any Salon pages without written permission is strictly prohibited
    Copyright 2005 Salon.com


    Salon, 22 4th Street, 16th Floor, San Francisco, CA 94103
    Telephone 415 645-9200 | Fax 415 645-9204
    E-mail | Salon.com Privacy Policy