Search  About Salon  Table Talk  Newsletters  Advertise in Salon  Investor Relations

 
 

Salon.com

[Arts & Entertainment][ Books ][ Comics ][ Mothers Who Think ][ News ][ People ][ Politics ][ Sex ][ Technology ][ Audio ]

Article Finder



 

Decoding the genome | 1, 2, 3, 4, 5, 6


Wilmut has always insistently opposed the cloning of human beings, and in this book he repeats that objection; he views human cloning as an unwarranted imposition on the new person brought into being. On the same grounds (except in the case of correcting single-gene diseases), Wilmut opposes attempts to enhance the human genome to promote any particular physical or mental quality.

His book, written with fellow Dolly project biologist Keith Campbell and science writer Colin Tudge, sets the record straight on the history and impetus behind cloning research, relates the scientific journey to the creation of Dolly and provides an insider's view of the cutting edge of biotechnology. But the core of the book is its final section, "The Age of Biological Control." Here Wilmut squarely confronts the dilemmas of an era in which, inevitably, we will achieve nearly total control over the creation and development of any and all biological organisms, including humans. While Celera Corp.'s Venter is right that we currently "don't know shit about biology," knowing all of it -- or close to all of it -- could happen within a few generations.



Cracking the Genome: Inside the Race to Unlock Human DNA

By Kevin Davies

The Free Press
288 pages
Nonfiction

Buy it


Genome: The Autobiography of a Species in 23 Chapters

By Matt Ridley

HarperCollins
352 pages
Nonfiction

Buy it


The Triple Helix: Gene, Organism and Environment

By Richard Lewontin

Harvard Univ. Press
192 pages
Nonfiction

Buy it


A Darwinian Left: Politics, Evolution and Cooperation

By Peter Singer

Yale Univ. Press
64 pages
Nonfiction

Buy it


Engineering the Human Germline: An Exploration of the Science and Ethics of Altering the Genes We Pass to Our Children

Edited by Gregory Stock and John Campbell

Oxford Univ. Press
208 pages
Nonfiction

Buy it


The Second Creation: Dolly and the Age of Biological Control

By Ian Wilmut Keith Campbell and Colin Tudge

Farrar, Straus and Giroux
320 pages
Nonfiction

Buy it



Print story


E-mail story


View Salon privately with SafeWeb


"Cloning and genetic engineering are conceptually linked," Wilmut explains, "because they are technically linked." The real purpose behind cloning, after all, was to allow for precise genetic alteration and duplication. The traditional path of a fertilized egg, Wilmut tells us, "is a hit-and-miss affair, offering only limited possibilities." "But when cells are cultured by the million, and laid out in a dish for months at a stretch," Wilmut says, "genetic engineers can work their full repertoire." What shall be done to these cells? Who shall decide?

In a chapter called "Cloning People," authored by Wilmut alone, the scientist looks at many of the perspectives found in the other books covered in this essay. He endorses Lewontin's argument for a more complex understanding of the interaction of genes, organisms and environments because "the genes operate in constant dialogue with their surroundings," which in turn affect how genes function. That's part of the reason even biological clones would still be different people.

In response to the libertarianism advocated by Ridley and deeply embedded in American culture, Wilmut suggests that when it comes to risk, we need to look beyond statistical calculations and ask, "Risk to whom?" and "Risk of what?" The manipulation of our genetics involves more than just one individual. Even basic genetic test results have implications for all the blood relatives of the person undergoing the test.

For this reason, Wilmut insists that market forces alone should not determine how genetic technologies get applied. "Worldwide, we may perceive a trend toward libertarianism," he observes, but "various societies in recent years have shown that they can resist new technologies of many kinds, whatever the market forces." He cites nuclear power, high-rises and genetically modified organisms as examples.

To his credit, Wilmut claims no greater authority for his positions than that of a well-informed citizen. These issues are human and moral and not merely scientific. Coauthor Tudge adds, in an individually penned epilogue, "How, in general, can we ensure that ... we don't stop scientists from following their noses -- but that on the other hand we are not encumbered with technologies that offend us, or lower our quality of life, or simply hand over life's controls to powerful companies?"

Wilmut, Campbell and Tudge don't pretend to have final answers. They urge that "if we are serious -- if we are not simply trying to score political points or to underplay what has been achieved so far -- then we should think in serious intervals of time." They suggest 200 to 500 years as the block of time during which the age of biological control will be realized. If they're right -- and unless we are satisfied with the alternatives offered by Ridley's libertarianism, Lewontin's interactive constructionism, Singer's consequentialism or Watson's naturalism -- then a book that helps us think in just those terms is the book that urgently needs to be written next.

 


salon.com

- - - - - - - - - - - -

About the writer
Ralph Brave is a science writer who lives in Davis, Calif.

Sound Off
Send us a Letter to the Editor

Related stories
Book of life?
Hosanna! The Human Genome Project has been completed. We will now cure diseases, weed out defective genes and create a new supergeneration in the near future. Not.
By Tabitha M. Powledge
06/27/00

The great gene race
A tiny private company and the giant public genome project jointly crossed the finish line. But the upstart really won.
By Ralph Brave
06/26/00

Who owns your DNA?
Genetic research that can save lives is often stymied by biotech companies' greedy patent claims.
By Arthur Allen
03/07/00

Salon.com >> Books
 


 



Don't get sunburned!  Cover up with a Salon T-shirt this summer.




Extra goodies and great services in
Salon Plus

____
 




 
 
____
 
   
 
____
 
  Current Stories
  • The history boy The 9-year-old narrator of the heartbreaking "When We Were Romans" flees family chaos through literature.
    By Laura Miller
  • How to read the James Wood way The fiercely talented critic takes us on an illuminating tour of fiction -- but there's a hole in his plot.
    By Louis Bayard
  • The good humor man Who invented jokes, and why do we laugh at them? Jim Holt discusses the history of funny.
    By James Hannaham
  • Answering terror with terror In "The Dark Side," Jane Mayer chronicles the terrible, destructive decisions the Bush administration made in the name of fighting terrorism.
    By Louis Bayard
  •  

    shim shim shim shim shim shim shim
    shim
    shim

    Maya Angelou reads from "The Heart of a Woman"

    shim
    shim



    Salon  Search  About Salon  Table Talk  Newsletters  Advertise in Salon  Investor Relations


    Arts & Entertainment | Books | Comics | Mothers Who Think | News
    People | Politics | Sex | Tech & Business and The Free Software Project
    Letters | Columnists | Salon Plus | Salon Shop


    Reproduction of material from any Salon pages without written permission is strictly prohibited
    Copyright 2005 Salon.com


    Salon, 22 4th Street, 16th Floor, San Francisco, CA 94103
    Telephone 415 645-9200 | Fax 415 645-9204
    E-mail | Salon.com Privacy Policy