Strictly speaking, anything could happen when Massachusetts voters go to the polls on Tuesday for a special election to replace the late Sen. Ted Kennedy.

Polls can, and will, be wrong — especially in the case of a special election, when the pollsters’ first task becomes figuring out a sample that gives something close to an accurate picture of the electorate that will actually vote. And in this race, given how improbable the idea that a Republican — a Republican! — could take over for the last of the great Kennedys once seemed, the notion that things could suddenly shift in Democrat Martha Coakley’s favor doesn’t seem so wild.

That said, though, looking at the race right now, it seems very likely that Republican Scott Brown will win. In doing so, he will cut the Senate Democratic Caucus down to 59 members, and he may well doom healthcare reform, at least for this year.

If nothing else, here’s what you need to know right now: FiveThirtyEight.com’s Nate Silver has spoken. And he, in his infinite, omniscient polling wisdom, sees a victory for Brown and the GOP. Brown is a 74 percent favorite to win the seat, according to Silver’s model.

“We have traditionally categorized races in which one side has between a 60 and 80 percent chance of winning as ‘leaning’ toward that candidate, and so that is how we categorize this race now: Lean GOP,” Silver writes of the race. And, to add insult to injury for the Democrats among his readership, Silver notes that his model “correctly predicted the outcome of all 35 Senate races in 2008.” (He does, however, observe that due to the fact this is a special election, “there is a higher-than-usual chance of large, correlated errors in the polling, such as were observed in NY-23 and the New Hampshire Democratic primary; the model hedges against this risk partially, but not completely.”)

Silver isn’t the only one who sees the race going in this direction. Stuart Rothenberg’s Rothenberg Political Report moved the race into its “Lean Takeover” — that is, Republican — category on Monday. And on Thursday, the Cook Political Report changed its classification of the election from “Lean Democrat” to “Toss Up.”

The reason for all this, and the pessimism coming from Democrats nationwide lately, is a series of polls that has come out recently showing a trend away from Coakley and towards Brown. As of this post, almost every single poll conducted on or since last Friday and included in Real Clear Politics’ roundup shows Brown with a lead. Only one, sponsored by Daily Kos, broke from the pack — and it just showed a tie.

One poll in particular got the most attention of any late Monday. Sponsored by Politico and conducted by InsiderAdvantage, it showed Brown with a pretty solid lead of nine percentage points, at 52 percent to Coakley’s 43 percent. (The margin of error was plus or minus 3.4 percentage points.) But InsiderAdvantage is run by a former aide to Newt Gingrich, and that’s a fact the Democratic National Committee jumped on when it moved, hard, to try to counter the poll was doing to Coakley’s media coverage.

In an e-mail to reporters, with a subject line of “Don’t Buy This Skewed Poll,” DNC spokesman Brad Woodhouse laid out his reasons to doubt the survey results:

1. It was conducted in one night – which is notoriously unreliable
2. It has a 20 percent Republican sample – which is 5-8 points more than most polls. Obviously skewing the sample more Republican than the electorate is – is going to skew the result in Brown’s favor.
3. The poll was conducted, and the charged quotes in the article are attributed to, a former aide to NEWT GINGRICH – which Politico pointed in the 6th paragraph.
4. Does anyone really believe – as this skewed poll shows – that Brown is going to win 77% of Hispanics and 26% of blacks? Those results alone should ring alarm bells about the accuracy of this poll.

Woodhouse’s first and last points undoubtedly had some validity to them, even if his second seemed lacking. (Part of Coakley’s problem is, after all, that Republican turnout seems like it’ll be higher than it might otherwise in Massachusetts, one of the bluest of states.) But given the general trend in polling for this race, it seems like it won’t be that easy for the DNC to get observers to write this particular survey off. More importantly, though she could of course still pull something out, it doesn’t seem like Coakely will be able to do much at this late date to prove the polls wrong.

There’s barely more than a weekend standing between us and Judgment Day for Massachusetts Democrats. On Tuesday, the state’s holding a special election to pick a replacement for the late Sen. Ted Kennedy, and the bases of both parties are apparently a-quiver with dread and anticipation, respectively.

You could guess it was going to be an intense final stretch yesterday, when a new poll came out from Suffolk University showing Republican Scott Brown leading Democratic nominee Martha Coakley by four percentage points, 50 percent to 46. That’s only the second poll to give Brown a lead, and the race is obviously too close to call — but still, trailing by four in Massachusetts can’t feel great for Democrats. As pollster David Paleologos put it, “It’s a Brown-out!”

Since Saturday, the group behind TeaPartyExpress.org has spent at least $32,000 supporting Scott Brown, the Republican candidate for the Massachusetts Senate seat, federal records show. Brown’s own campaign Web site highlights a fundraiser held a couple weeks ago called the “Friends of the Tea Party Scott Brown reception,” where paying $500 earned supporters the label “American Revolutionary” (for a mere 25 bucks, you could be a “Patriot”). The conservative blogs that help fuel the tea party movement have been abuzz over Brown for weeks, eager to see the GOP candidate pull an upset win over Democrat Martha Coakley.

As the Massachusetts Senate special election wraps up, a couple of unsavory right-wing groups are coming to Republican candidate Scott Brown’s aid — underscoring just how conservative the GOP nominee who’s suddenly causing Bay State Democrats to panic really is.

Brown was endorsed Wednesday by Americans for Legal Immigration PAC, one of the most aggressive organizations against illegal immigration in the country (the group runs a Web page where it encourages people to “report illegal immigrants, employers that hire illegal labor, and smugglers”). Officials say ALIPAC is backing Brown “due to his campaign’s focus on the issue of the illegal immigration.” The endorsement may not be entirely welcome news; the Southern Poverty Law Center points out that the group is aligned with the Federation for American Immigration Reform, which the SPLC claims is a hate group. (FAIR vehemently disputes that charge.)