In one instance in February, Lori drew an extended analogy between the mandate to cover contraception and a hypothetical mandate forcing all restaurants nationwide to serve pork, saying it is “absurd for someone to come into a kosher deli and demand a ham sandwich.”

Lori, 60, was born in Louisville, Ky., and ordained a priest in 1977. He became a bishop in 1995 and has served as Bishop of Bridgeport since 2001. He oversaw a diocese that includes more than 460,000 Catholics.

The Archdiocese of Baltimore serves 510,000 Catholics in Baltimore and nine counties in central and western Maryland. The post is considered a prominent one because it is the first Catholic diocese in the United States, established in 1789. Four of the men who have held the post have gone on to become cardinals.

In a statement released Tuesday, Lori said the “very thought of serving and leading the Nation’s Premier See fills me with joy and also with profound gratitude.”

Lori has a bachelor’s degree from the now-closed Seminary of Saint Pius X in Erlanger, Ky., and a master’s degree from Mount Saint Mary’s Seminary in Emmitsburg. He received a doctorate from The Catholic University of America in Washington and has served on several committees of the United States Conference of Catholic Bishops.

His assignment to Baltimore will not be the first time Lori has served in Maryland. His first assignment was as an associate pastor of Saint Joseph Parish in Landover.

He is a fan of classic cars and television shows from the 1960s. At one point he had dogs named Barnes and Noble.

Lori will succeed Cardinal Edwin O’Brien, who served as Baltimore’s 15th archbishop from October 2007 to August 2011 when he was named grand master of the Equestrian Order of the Holy Sepulchre of Jerusalem.

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Associated Press reporter Jessica Gresko contributed to this story.

The Block is a neighborhood of strip clubs with gaudy lights, including Larry Flynt’s Hustler Club. Some of the venues are historic theaters.

Joanna Trela, 38, an office manager for a law firm, works on the 27th floor of a building overlooking the fire scene. She said she looked out the window and spotted the fire after an attorney in her firm suggested that something was wrong with the ventilation system.

“We smelled it,” Trela said.

The fire had her temporarily stranded.

“The most frustrating part is, they shut down the parking garage, so nobody in our building can leave, so we’re all kind of hanging out,” Trela said.

Pardus pulled a semiautomatic gun from his waistband and shot the doctor once, the commissioner said. The doctor, identified by colleagues as orthopedic surgeon David B. Cohen, collapsed outside the eighth-floor room where Pardus’ mother, Jean Davis, was being treated.

Pardus then holed up in the room in a more than two-hour standoff that led authorities to lock down a small section of the Nelson Building while allowing the rest of the sprawling red-brick medical complex — a cluster of hospital, research and education buildings — to remain open.

When officers made their way to the room, they found Pardus and his mother shot to death, he on the floor, she in her bed.

Bealefeld said he did not know what the woman was being treated for at Hopkins, a world-class institution widely known for its cancer research and treatment. It is part of Johns Hopkins University, which has one of the foremost medical schools in the world.

Michelle Burrell, who works in a coffee shop in the hospital lobby, said she was told by employees who were on the floor where the doctor was shot that the gunman was angry with the doctor’s treatment of his mother.

“It’s crazy,” she said.

Pardus was from Arlington, Va., and had a handgun permit in that state, police said. The gunman was initially identified as Warren Davis, but police later said that was an alias.

The wounded doctor, an assistant professor at the medical school, underwent surgery.

“The doctor will be OK,” police spokesman Anthony Guglielmi said. “He’s in the best place in the world — at Johns Hopkins Hospital.”

With more than 30,000 employees, the Johns Hopkins medical system is Baltimore’s biggest private employer. The hospital has more than 1,000 beds and more than 1,700 full-time doctors.

The Nelson Building is the main hospital tower. The eighth floor is home to orthopedic, spine, trauma and thoracic services.

Hopkins said it informed its employees about the gunman in an e-mail at 11:30 a.m., about a half-hour after the doctor was shot. They were told to remain in their offices or rooms with the doors locked and to stay away from the windows. At 1:30 p.m., another e-mail went out advising employees that police “are in control of the situation.”

As the standoff dragged on, people with appointments in other parts of the hospital were encouraged to keep them.

Hannah Murtaugh, 25, a first-year student at the nursing school, said her physiology class in an adjacent building was put on lockdown. She said a classmate received a text-message warning from the school about a gunman in the Nelson Building. Her professor interrupted the lecture to let students know.

“They just kept telling us to stay away from the windows,” she said. “I was scared — wondering if any of my friends or other students who had clinicals that day were on that floor, hoping the situation would be contained, trying to see what was going on while staying away from the windows.”

She said security personnel helped keep everyone calm and made sure doors were locked.

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Associated Press writers Ben Nuckols and Kathleen Miller in Baltimore and Medical Writer Marilynn Marchione in Milwaukee contributed to this report.

He said he did not know what the woman was being treated for.

Davis then pulled a semiautomatic handgun from his waistband shot the doctor once in the abdomen, the commissioner said. After that, Davis holed up in his mother’s hospital room for two hours.

When officers made their way to room 873, they found Warren Davis dead on the floor and his mother dead in her hospital bed.

The doctor, who collapsed just outside the room, underwent surgery and is expected to survive, police said. His name has not been released by police or the hospital.

Michelle Burrell, who works in a coffee shop in the hospital lobby, said she was told by employees who were on the floor where the doctor was shot that the gunman was angry with the doctor’s treatment of his mother.

“Basically, he was upset about his mother being paralyzed by the doctor,” Burrell said. “It’s crazy.”

A small area of the hospital had been locked down before the gunman died, as about a dozen officers wearing vests and helmets and carrying assault weapons prepared to go into the hospital at midday. Police spokesman Anthony Guglielmi said the gunman had not taken any hostages, and people with appointments in other parts of the hospital were encouraged to keep them.

The FBI was assisting Baltimore police, said FBI spokesman Richard J. Wolf.

The gunman was on the 8th floor of the Nelson building, the main hospital tower. According to the Hopkins website, the eighth floor is home to orthopedic, spine, trauma and thoracic services.

Guglielmi said the situation was contained to that part of the hospital, and no people had been locked in rooms or otherwise in danger.

The rest of the massive hospital, research and medical education complex remained open, including the emergency department.

With more than 30,000 employees, Johns Hopkins Medicine is among Maryland’s largest private employers and the largest in Baltimore. The hospital has more than 1,000 beds and more than 1,700 full-time doctors.

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Associated Press writers Ben Nuckols and Kathleen Miller contributed to this report.