The newest "Star Trek" spinoff, Enterprise (8 p.m., UPN), has its two-hour premiere. Scott Bakula is Capt. Jonathan Archer in this prequel set a century before Capt. Kirk took the Enterprise into deep space. The reality series Lost (8 p.m., NBC) returns with its second episode; contestants are stranded in the middle of nowhere and compete to make it back to the Statue of Liberty. The West Wing (9 p.m., NBC) is not having its season premiere tonight; instead, it's a rerun of last year's Christmas episode. A special "West Wing" episode about the terrorist attack runs Oct. 3; the season officially opens Oct. 10. The Drew Carey Show (9 p.m., ABC) opens its new season; so does Law & Order (10 p.m., NBC), which features a "ripped from the headlines" case about a woman killed by a vicious dog.
Braves at Marlins (7 p.m., ESPN)
Cardinals at Astros (8 p.m., ESPN2)
Giants at Dodgers (10 p.m., ESPN)
Rosie O'Donnell (syndicated) Regis Philbin, Linda Ellerbee, Usher
David Letterman (CBS) Ben Stiller, Tenacious D
Jay Leno (NBC) Megan Mullally, Train
Politically Incorrect (ABC) Eric McCormack, Lynn Redgrave
Craig Kilborn (CBS) James Cromwell, Melissa George
All times Eastern unless noted.