On Buffy the Vampire Slayer (8 p.m., UPN), the three geeks -- Jonathan, Warren and Andrew -- begin their quest for world domination. Big Pussy alert: Vincent Pastore of "The Sopranos" guests on Emeril (8 p.m., NBC) -- not that that's a reason to watch this loser sitcom. Nova (8 p.m., PBS, check local listings) presents "Secrets of the Mind," a look at a neurologist's case files. Lorelai and Rory hit the road for a visit to Harvard on Gilmore Girls (8 p.m., WB). Juliette Lewis plays Dharma's best friend from childhood on Dharma & Greg (8 p.m., ABC).
Music and haute couture meet at the VH1/Vogue Fashion Awards (9 p.m., VH1). Alicia Keys is among the performers.
Sharks at Sabres (8 p.m., ESPN2)
Rosie O'Donnell (syndicated) Kevin Kline
David Letterman (CBS) Bruce Willis, Alicia Keys (rerun)
Jay Leno (NBC) Tim Allen, Charlotte Church (rerun)
Politically Incorrect (ABC) Jason Alexander, David Crosby
Conan O'Brien (NBC) Tom Selleck, Black Crowes (rerun)
Craig Kilborn (CBS) Ted Danson, Natasha Gregson-Wagner (rerun)
All times Eastern unless noted.